The vaccine Research Centre – Bacterial Vaccine was started on 01-04-1991 by converting the "Frozen Semen Technique Scheme" functioning under the Centre for Animal Health Studies, TANUVAS into a new plan scheme entitled as "Establishment of vaccine Research Centre Unit on Bacterial Vaccine". Now the lab has been established at the second floor of the Central University Laboratory building in September 2015 with university funding.
OBJECTIVES
Improvement of existing and new bacterial vaccines of livestock and poultry
Development of Heat killed Johne's disease vaccine for Cattle and sheep.
Achivements
Developed a Modified vaccine against Black Quarter
Developed an Autogenous Inactivated vaccine against Fowl Cholera in poultry
Developed a biofilm based autogenous vaccine against fowl cholera in poultry
Developed a combined vaccine against Haemorrhagic septicemia and Black Quarter
Developed an inactivated vaccine against Johne's disease for Cattle, sheep and Goat
Developed an autogenous vaccine against Mannheimia haemolytica for Japanese Quail
Snuffles vaccine for rabbits
Developed an autogenous vaccine against Pasteurella multocida vaccine for ducks
Technology Transfered
Modified Black Quarter Vaccine - IVPM, Ranipet on 1999
Filed for Autogenous Fowl Cholera vaccine – IPR/4.14.20/10047 of NRDC, NewDelhi.
Research
Research Schemes Completed
An ICAR scheme on "Development of combined vaccine for Haemorrhagic septicemia and Black Quarter" was completed from 2005 to 2008
A NADP Project on "Novel diagnostics and vaccine delivery system for emerging and economically important bacterial and viral diseases affecting small ruminants" is functioning in this unit from 2010 – 2011
A NADP Project on "Novel diagnostics and vaccine delivery system for emerging and economically important bacterial and viral diseases affecting small ruminants" is functioning in this unit from 2011 – 2012
A project on "A study on the prevalence of Mannheimia haemolytica in cattle and buffaloes in India" funded by Pfizer Pvt. Ltd., India
Colloborative Research Projects Completed
A clinical trial with nanoparticles loaded with gentamicin to treat Brucella infected animals was conducted in collaboration with Virginia Tech, USA
Under Indo US research project in collaboration with Virginia Tech, USA a " Clinical trial with Myoconda® in naturallt Mycobacterium avium subsp. paratuberculosis infected small ruminants " was carried out
Ongoing Research Schemes
DBT funded project on “Validation, Regulatory compliance and translation of vaccine and molecular diagnostics for Duck Plague” for Rs.43.46 lakhs for 3 years from 31.03.21
DBT funded project on “Development of DIVA diagnostics and marker vaccine against Duck Plague Virus” for Rs.24.87 lakhs for 3 years from 25.09.18 to 24.09.21
DBT funded project on “An Integrated Approach to explore and exploit the innate and adaptive immune response in Indigenous Duck Breeds of North Eastern and South India” for Rs.20.47 lakhs for 3 years from 25.09.18 to 24.09.21
DBT-NER funded project on “Genetic Characterization of Antibiotic Resistance in Clostridium perfringens and Clostridium difficile and their Public Health Significance” for Rs.35.93 lakhs for 3 years from 23.05.18 to 22.11.21
Facilities Available
Deep Freezer-20 degree C
Deep Freezer-80 degree C
Class III Bio-safety cabinet
Class II & I Laminar flow
Nikon Microscope
Electronic Balance
Cooling Centrifuge
Incubator
ELISA Reader
ELISA Washer
Autoclave vertical
Thermal cycler
Anaerobic Chamber
Carbon Dioxide Incubator
Vaccine available at VRC-BV for sale
S. No.
Vaccine
Cost (Rs.)/ Dose
1
Autogenous Fowl Cholera vaccine for chicken
1.20
2
Autogenous Mannheimia haemolytica vaccine for Quaills
0.60
3
Autogenous vaccine for Snuffles in rabbits
1.20
4
Autogenous Duck Pasteurellosis vaccine
1.20
FACULTY
Dr. S. Manoharan, Professor
Dr. M. Latha Mala Priyadharshini, Assistant Professor
Professor and Head,
Vaccine Research Centre-Bacterial Vaccines,
Centre for Animal Health Studies, TANUVAS,
Madhavaram Milk Colony, Chennai – 600051.
Phone: +91-44-2555 1544
E-mail: vrcbv@tanuvas.org.in
